Olvanil

Key Product Details

Product Description

Olvanil is a potent vanilloid receptor agonist (pEC₅₀ values are 8.1 and 7.7 at rat and human VR1 receptors respectively). Also blocks anandamide uptake (IC₅₀ = 9 μM) and may bind to CB₁ cannabinoid receptors. Antinociceptive following systemic administration.

Product Specifications for Olvanil

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Olvanil

The following data is based on the product molecular weight 417.63.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

4 3 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.39 mL	11.97 mL	23.94 mL
5 mM	0.48 mL	2.39 mL	4.79 mL
10 mM	0.24 mL	1.20 mL	2.39 mL
50 mM	0.05 mL	0.24 mL	0.48 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 24 publications citing the usage of this product.

• Ralevic Cannabinoid activation of recombinant and endogenous vanilloid receptors. Eur.J.Pharmacol. 2001 PMID: 11672565
• Dray NE-19550 and NE-21610, antinociceptive capsaicin analogues: studies on nociceptive fibres of the neonatal rat tail in vitro. Eur.J.Pharmacol. 1990 PMID: 2384136
• Janusz Vanilloids. 1. Analogs of capsaicin with antinociceptive and antiinflammatory activity. J.Med.Chem. 1993 PMID: 8410971
• Di Marzo Interactions between synthetic vanilloids and the endogenous cannabinoid system. FEBS Lett. 1998 PMID: 9801167

Product Documents for Olvanil