OMDM-2

Key Product Details

Product Description

OMDM-2 is a metabolically stable inhibitor of anandamide cellular uptake (K_i = 3 μM). Displays relatively low affinity for CB₁ and CB₂ receptors (K_i values are 5.1 and > 10 μM) and for vanilloid VR1 receptors (EC₅₀ = 10 μM). FABP inhibitor. Has minimal activity against FAAH (K_i > 50 μM). Active in vivo.

Product Specifications for OMDM-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for OMDM-2

The following data is based on the product molecular weight 431.66.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.17 mL	115.83 mL	231.66 mL
0.5 mM	4.63 mL	23.17 mL	46.33 mL
1 mM	2.32 mL	11.58 mL	23.17 mL
5 mM	0.46 mL	2.32 mL	4.63 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

• de Lago In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake. Eur.J.Pharmacol. 2004 PMID: 14744610
• Deutsch A personal retrospective: Elevating Anandamide (AEA) by targeting fatty acid amide hydrolase (FAAH) and the fatty acid binding proteins (FABPs). Front.Pharmacol. 2016 PMID: 27790143
• Ortar Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem.Pharmacol. 2003 PMID: 12732359

Product Documents for OMDM-2