Catalog Number: 1797
Chemical Name: (9Z)-N-[1-((R)-4-Hydroxbenzyl)-2-hydroxyethyl]-9-octadecenamide
Biological Activity
Metabolically stable inhibitor of anandamide cellular uptake (Ki = 3 μM). Displays relatively low affinity for CB1 and CB2 receptors (Ki values are 5.1 and > 10 μM) and for vanilloid VR1 receptors (EC50 = 10 μM). Has minimal activity against FAAH (Ki > 50 μM). Active in vivo.
Technical Data
  • M.Wt:
    431.66
  • Formula:
    C27H45NO3
  • Solubility:
    Soluble to 10 mM in ethanol and to 10 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at +4°C
  • CAS No:
    616884-63-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Novel selective and metabolically stable inhibitors of anandamide cellular uptake.
    Ortar et al.
    Biochem.Pharmacol., 2003;35:1473
  2. In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake.
    de Lago et al.
    Eur.J.Pharmacol., 2004;484:249
Citations:

The citations listed below are publications that use Tocris products. Selected citations for OMDM-2 include:

1 Citations: Showing 1 - 1

  1. Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension.
    Authors: Bátkai Et al.
    FASEB J 2004;110:1996

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