Ondansetron hydrochloride

  ( 4 citations )    
Product Datasheet
Catalog Number:2891
Alternate Names:GR 38032
Chemical Name:1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride
Product Details
Citations (4)
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Reviews
Biological Activity
Selective 5-HT3 receptor antagonist (Ki = 6.16 nM). Antiemetic; prevents emesis induced by cytotoxic drugs and radiation.
Technical Data
  • M.Wt:
    329.83
  • Formula:
    C18H19N3O.HCl
  • Solubility:
    Soluble to 50 mM in water and to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    99614-01-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Ondansetron hydrochloride include:

4 Citations: Showing 1 - 4
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  1. Low protein diets produce divergent effects on energy balance.
    Authors: Pezeshki Et al.
    PLoS One  2016;6:25145
  2. Galanin-Mediated Behavioural Hyperalgesia from the Dorsomedial Nucleus of the Hypothalamus Involves Two Independent Descending Pronociceptive Pathways.
    Authors: Amorim Et al.
    Antioxid Redox Signal  2015;10:e0142919
  3. Ginger and its pungent constituents non-competitively inhibit serotonin currents on visceral afferent neurons.
    Authors: Jin Et al.
    Korean J Physiol Pharmacol  2014;18:149
  4. Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): evidence for TRPA1-independent effects.
    Authors: Capasso Et al.
    Br J Pharmacol  2012;165:1966

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