Catalog Number: 0483
Chemical Name: 3,5-Dinitrocatechol
Biological Activity
Potent and selective inhibitor of catechol-O-methyl-transferase.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in ethanol and to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Rationale for selective COMT inhibitors as adjuncts in the drug treatment of Parkinson's disease.
    Mannisto and Kaakola
    Pharmacol.Toxicol., 1990;66:317
  2. Catechol-O-methyltransferase-inhibiting pyrocatechol derivatives: synthesis and structure-activity studies.
    Borgulya et al.
    Helv.Chim.Acta, 1989;72:952

The citations listed below are publications that use Tocris products. Selected citations for OR-486 include:

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  1. Estradiol increases cAMP in the oviductal secretory cells through a nongenomic mechanism.
    Authors: Oróstica Et al.
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