OR-486

Catalog # Availability Size / Price Qty
0483/50
Cat.No. 0483 - OR-486 | C6H4N2O6 | CAS No. 7659-29-2
1 Image
Description: COMT inhibitor

Chemical Name: 3,5-Dinitrocatechol

Purity: ≥99%

Product Details
Citations (2)
Reviews

Biological Activity

Potent and selective inhibitor of catechol-O-methyl-transferase.

Technical Data

M.Wt:
200.11
Formula:
C6H4N2O6
Solubility:
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
7659-29-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Rationale for selective COMT inhibitors as adjuncts in the drug treatment of Parkinson's disease.
    Mannisto and Kaakola
    Pharmacol.Toxicol., 1990;66:317
  2. Catechol-O-methyltransferase-inhibiting pyrocatechol derivatives: synthesis and structure-activity studies.
    Borgulya et al.
    Helv.Chim.Acta, 1989;72:952

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for OR-486

The citations listed below are publications that use Tocris products. Selected citations for OR-486 include:

2 Citations: Showing 1 - 2

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for OR-486

There are currently no reviews for this product. Be the first to review OR-486 and earn rewards!

Have you used OR-486?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.