Chemical Name: 3,5-Dinitrocatechol
Biological ActivityOR-486 is a potent and selective inhibitor of catechol-O-methyl-transferase.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Rationale for selective COMT inhibitors as adjuncts in the drug treatment of Parkinson's disease.
Mannisto and Kaakola
Catechol-O-methyltransferase-inhibiting pyrocatechol derivatives: synthesis and structure-activity studies.
Borgulya et al.
Citations for OR-486
The citations listed below are publications that use Tocris products. Selected citations for OR-486 include:
2 Citations: Showing 1 - 2
Persistent catechol-O-methyltransferase-dependent pain is initiated by peripheral β-andrenergic receptors.
Authors: Ciszek Et al.
OE increases cAMP in the oviductal secretory cells through a nongenomic mechanism.
Authors: Oróstica Et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for OR-486
There are currently no reviews for this product. Be the first to review OR-486 and earn rewards!
Have you used OR-486?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image