Biological ActivityPotent and selective inhibitor of catechol-O-methyl-transferase.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Rationale for selective COMT inhibitors as adjuncts in the drug treatment of Parkinson's disease.
Mannisto and Kaakola
Catechol-O-methyltransferase-inhibiting pyrocatechol derivatives: synthesis and structure-activity studies.
Borgulya et al.
Citations for OR-486
The citations listed below are publications that use Tocris products. Selected citations for OR-486 include:
2 Citations: Showing 1 - 2
Persistent catechol-O-methyltransferase-dependent pain is initiated by peripheral β-andrenergic receptors.
Authors: Ciszek Et al.
OE increases cAMP in the oviductal secretory cells through a nongenomic mechanism.
Authors: Oróstica Et al.
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