Orexin B (mouse)

Tocris Bioscience | Catalog # 1457

Endogenous agonist at OX1 and OX2
Tocris Bioscience

Key Product Details

Description

Endogenous agonist at OX1 and OX2
View all Orexin Receptor Agonists »

Product Description

Orexin B (mouse) is an endogenous agonist at orexin receptors. May be involved in the regulation of feeding, sleep-wake cycle and other hypothalamic functions. Orexin B exerts excitatory effects on nigral dopaminergic neurons and alleviates motor symptoms in a Parkinson's disease mouse model.

Product Specifications for Orexin B (mouse)

Molecular Weight

2936.43

Formula

C126H215N45O34S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

202801-92-1

PubChem ID

90479795

InChI Key

RLVZFBVFVIDDPQ-GWQFQBPDSA-N

SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

Product Documents for Orexin B (mouse)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Orexin B (mouse)

For research use only

Citations for Orexin B (mouse)

Customer Reviews for Orexin B (mouse) (1)

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  • High quality peptide
    Name: Samanta Grella
    Species: Mouse
    Assay Type: In Vitro
    Verified Customer | Posted 11/18/2022
    This is the second Tocris peptide we have used in our study. The first one was from human origin (product #1456). Because a colleague suggested us to repeat the experiment with a peptide from mouse origin; we have chosen this product (Orexin B mouse). The results were amazing because the neuronal activation has increased at a level we were expecting to conduct the behavioural analysis. As shown in the attached graph, this compound stimulated neuronal activity at a hippocampus nuclei, as measured by immunoflurescence after compound delivery into the brain. We are very satisfied with the result and I recommed this Tocris product.
    Orexin B (mouse) 1457

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