Biological Activity Positive allosteric modulator and at higher concentrations direct agonist of GABAA receptors (EC50 = 1.1 μM). Also displays positive modulation of glycine receptors (EC50 = 22.9 μM). Anesthetic steroid; induces hypnosis and loss of righting reflexes in mice.
Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
Store at RT
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