Org 20599

   
Product Datasheet
Catalog Number:2738
Chemical Name:(2β,3α,5α)-21-Chloro-3-hydroxy-2-(4-morpholinyl)pregnan-20-one
Product Details
Reviews
Biological Activity
Positive allosteric modulator and at higher concentrations direct agonist of GABAA receptors (EC50 = 1.1 μM). Also displays positive modulation of glycine receptors (EC50 = 22.9 μM). Anesthetic steroid; induces hypnosis and loss of righting reflexes in mice.
Technical Data
  • M.Wt:
    438.04
  • Formula:
    C25H40ClNO3
  • Solubility:
    Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
  • Storage:
    Store at RT
  • CAS No:
    156685-94-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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