Catalog Number: 5127
Chemical Name: N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanyl-O-(ethenylsulfonyl)-N-4-pentyn-1-yl-L-tyrosinamide
Biological Activity
Protein disulfide isomerase (PDI) inhibitor (IC50 = 1.7 μM). Inhibits proliferation of numerous cancer cell lines. Cell permeable.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization.
    Xu et al.
    PLoS One, 2013;8:e76657
  2. Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase
    Ge et al.
    ACS Chem.Biol., 2013;8:2577
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