Protein disulfide isomerase (PDI) inhibitor (IC50
= 1.7 μ
M). Inhibits proliferation of numerous cancer cell lines. Cell permeable.
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All Tocris products are intended for laboratory research use only.
Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization.
Xu et al.
PLoS One, 2013;8:e76657
Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase
Ge et al.
ACS Chem.Biol., 2013;8:2577