p53R2 Antibody Pair [HRP]

Novus Biologicals | Catalog # NBP2-79410

Novus Biologicals
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Key Product Details

Assay Type

Sandwich ELISA

Assay Range

46.88-3000 pg/ml (example only; lot dependent)

Sensitivity

47 pg/ml (example only; lot dependent)

Reactivity

Human
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Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Human p53R2.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for p53R2 Antibody Pair [HRP]

Sandwich ELISA: p53R2 Antibody Pair [HRP] [NBP2-79410] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for p53R2 Antibody Pair [HRP]

  • Mouse Monoclonal Capture Antibody
  • Mouse Monoclonal Detection Antibody (HRP-conjugated)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: p53R2

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and g-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumour suppression.

Alternate Names

RRM2B

Gene Symbol

RRM2B

Additional p53R2 Products

Product Documents for p53R2 Antibody Pair [HRP]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for p53R2 Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Related Research Areas

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