PALB2 Antibody

Novus Biologicals | Catalog # NBP3-12329

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit
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Product Specifications

Immunogen

Synthetic peptide taken within amino acid region 1,130-1,186 on human PALB2 protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for PALB2 Antibody

Western Blot: PALB2 Antibody [NBP3-12329]

Western Blot: PALB2 Antibody [NBP3-12329]

Western Blot: PALB2 Antibody [NBP3-12329] - 1:500 antibody dilution in DiluObuffer. Apparent MW is 131 KDa.
Immunohistochemistry-Paraffin: PALB2 Antibody [NBP3-12329]

Immunohistochemistry-Paraffin: PALB2 Antibody [NBP3-12329]

Immunohistochemistry-Paraffin: PALB2 Antibody [NBP3-12329] - Rat small intestine. 1:50 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.

Applications for PALB2 Antibody

Application
Recommended Usage

ELISA

1:10000

Immunohistochemistry

1:50-1:150

Immunohistochemistry-Paraffin

1:50-1:150

Immunoprecipitation

1:200

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: PALB2

PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.

Long Name

Partner and Localizer of BRCA2

Alternate Names

FANCN

Gene Symbol

PALB2

Additional PALB2 Products

Product Documents for PALB2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PALB2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

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