Pam2CSK4 Biotin
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Description: Biotinylated Pam2CSK4 (Cat. No. 4637)
Biological Activity
Biotinylated Pam2CSK4 (Cat. No. 4637), a Toll-like receptor 2/6 agonist.Technical Data
Formula:
C87H162N14O16S2
Sequence:
CSKKKK
(Modifications: Cys = S-[2,3-Bis(palmitoyloxy)-(2-R)-propyl]-Cys), K6= aminocaproic acid-amonocaproic acid-biotin
Solubility:
Soluble to 1 mg/ml in 20% acetonitrile - 0.1% acetic acid
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
-
Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Latz et al.
Nat.Immunol., 2007;8:772
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