PAMP-12 (human, porcine)

Name: PAMP-12 (human, porcine)
Brand: Tocris Bioscience
SKU: 6551
Price: 204 USD
Availability: InStock

Tocris Bioscience | Catalog # 6551

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Product Documents

Potent MRGPRX2 agonist

Technical Data
Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Potent MRGPRX2 agonist

Product Description

PAMP-12 (human, porcine) is a potent endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC₅₀ = 57.2 nM). Corresponds to amino acids 9 to 20 of proadrenomedullin.

Product Specifications for PAMP-12 (human, porcine)

Molecular Weight

1618.95

Formula

C₇₇H₁₁₉N₂₅O₁₄

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

196305-05-2

PubChem ID

16137959

InChI Key

DNUWKYBPCFUDDK-DYQOJKGJSA-N

SMILES

[H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product.

Lansu In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat.Chem.Biol. 2017 PMID: 28288109
Kamohara Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides. Biochem.Biophys.Res.Commun. 2005 PMID: 15823563

Product Documents for PAMP-12 (human, porcine)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for PAMP-12 (human, porcine)

For research use only

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