7 results for "Mas-Related G Protein Coupled Receptor Agonists" in Products
Mas-Related G Protein Coupled Receptor Agonists
Mas-related G protein-coupled receptors (MRGPRs) are a family of orphan GPCRs, subdivided into nine separate subfamilies (A-H and X). They are found in mammalian species, with families A, B, C and H present only in rodents, the X subfamily only in primates, including humans, and families D to G conserved across mammalian species. The MRGPRX family consists of four distinct receptors: MRGPRX1 was previously known as sensory neuron-specific receptor (SNSR) 4 and MRGPRX3 was previously named SNSR1.
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Endogenous neuropeptide; binds sst1 - sst5, ghrelin receptor and MRGPRX2
| Alternate Names: | CST-14 |
| Purity: | ≥95% |
Potent MRGPRX1 agonist
| Purity: | ≥95% |
Potent C5a receptor antagonist
| Purity: | ≥95% |
MRGPRX2 agonist; also non-competitive nAChR antagonist
| Purity: | ≥95% |
Potent MRGPRX2 agonist
| Purity: | ≥95% |
Kir6 (KATP) blocker; displays high affinity for SUR1/Kir6.2 channels
| Alternate Names: | A-4166,Senaglinide |
| Chemical Name: | N-[[4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine |
MRGPRX2 agonist
| Chemical Name: | (3R)-N,N-Dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3-pyrrolidinamine |
| Purity: | ≥98% |
