Catalog Number: 5871
Chemical Name: 4-Chloro-DL-Phenylalanine methyl ester hydrochloride
Biological Activity
Tryptophan hydroxylase inhibitor. Inhibits 5-HT synthesis. Depletes 5-HT levels in orbitofrontal cortex and impairs reversal learning in rats. Methyl ester of p-Chlorophenylalanine (Cat. No. 0938).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test.
    Pinto Brod et al.
    Prog.Neuropsychopharmacol.Biol.Psychiatry., 2016;65:201
  2. Vortioxetine restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats.
    Wallace et al.
    Int.J.Neuropsychopharmacol., 2014;17:1695
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