Potent, selective, non-peptide angiotensin AT2
receptor antagonist. IC50
values are 34 and 210 nM in rat adrenal tissue and brain respectively.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Modulation of angiotensin II binding affinity by allosteric interaction of polyvinyl sulfate with an intracellular domain of the DuP-753-sensitive angiotensin II receptor of bovine adrenal glomerulosa.
Boulay et al.
Synthesis and structure-activity relationships of a novel series of non-peptide angiotensin II receptor binding inhibitors specific for the AT2 subtype.
Blankley et al.
Induction of angiotensin II subtype 2 receptor-mediated blood pressure regulation in synthetic diet-fed rats.
Tamura et al.
The citations listed below are publications that use Tocris products. Selected citations for PD 123319 ditrifluoroacetate include:
Showing Results 1 - 10 of 18