Catalog Number: 1243
Chemical Name: (4aR,10bR)-3,4a,4,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol hydrochloride
Biological Activity
Potent D3 dopamine receptor agonist (Ki = 2.3 nM). Displays 18 - 200-fold selectivity over other dopamine receptor subtypes.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 10 mM in water
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The behavioural and neurochemical profile of the putative dopamine D3 receptor agonist, (+)-PD 128907, in the rat.
    Bristow et al.
    Neuropharmacology, 1996;35:285
  2. Neurochemical and functional characterization of the preferentially selective dopamine D3 agonist PD 128907.
    Pugsley et al.
    J.Pharmacol.Exp.Ther., 1995;275:1355
  3. Atypical antipsychotic-like effects of the dopamine D3 receptor agonist (+)-PD 128907.
    Witkin et al.
    Eur.J.Pharmacol., 1998;347:R1
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