PD 168077 maleate

Catalog # Availability Size / Price Qty
1065/10
1065/50
PD 168077 maleate | CAS No. 630117-19-0 | Dopamine D4 Receptor Agonists
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Description: High affinity, selective D4 agonist

Chemical Name: N-[[4-(2-Cyanophenyl)-1-piperazinyl]methyl]-3-methylbenzamide maleate

Purity: ≥98%

Product Details
Citations (7)
Reviews

Biological Activity

PD 168077 maleate is a potent D4 dopamine receptor agonist (Ki = 8.7 nM) with > 400-fold selectivity over D2 and > 300-fold selectivity versus D3 subtypes respectively. Induces synaptic translocation of CaMK II to postsynaptic sites in cultured prefrontal cortical neurons. Centrally active in vivo.

Technical Data

M.Wt:
450.49
Formula:
C20H22N4O.C4H4O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
630117-19-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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