PD 168568 dihydrochloride
Chemical Name: 3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-one dihydrochloride
Biological ActivityPotent and selective dopamine D4 receptor antagonist (Ki values are 8.8 and 1842 nM at D4 and D2 receptors respectively). Reverses amphetamine-stimulated locomotion in vivo and is orally active.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Isoindolinone enantiomers having affinity for the DA D4 receptor.
Belliotti et al.
Citation for PD 168568 dihydrochloride
The citations listed below are publications that use Tocris products. Selected citations for PD 168568 dihydrochloride include:
1 Citation: Showing 1 - 1
Intravitreally-administered DA D2-like (and D4), but not D1-like, receptor agonists reduce form-deprivation myopia in tree shrews.
Authors: Ward Et al.
Vis Neurosci 2017;34:E003
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