Catalog Number: 4824
Chemical Name: N-[5-[3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl]-1,3,4-oxadiazol-2-yl]-4-morpholineethanamine
Biological Activity
Inhibitor of MEK1. Analog of PD 184352 (Cat. No. 4237).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in ethanol
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Targeting cancer with small molecule kinase inhibitors.
    Zhang et al.
    Nat.Rev.Cancer, 2009;9:28
  2. Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel competitive kinase inhibition.
    Ohren et al.
    Nat.Struct.Mol.Biol., 2004;11:1192
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