PDE11A Antibody

Novus Biologicals | Catalog # NBP3-12443

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit
View all PDE11A Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide taken within amino acid region 100-150 on PDE11A protein. Phosphorylated Ser 117 & 124.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for PDE11A Antibody

Western Blot: PDE11A Antibody [NBP3-12443]

Western Blot: PDE11A Antibody [NBP3-12443]

Western Blot: PDE11A Antibody [NBP3-12443] - Lane 1- Rat testis, Lane 2-Rat liver (negative control). 1:250 dilution in DiluObuffer. 1 hour incuabation at room temeperature. Apparent MW is 112.2 KDa on 7% SDS-PAGE.

Applications for PDE11A Antibody

Application
Recommended Usage

ELISA

1:10000

Immunoprecipitation

1:250

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: PDE11A

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Long Name

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

Alternate Names

EC 3.1.4.35, EC 3.1.4.53

Gene Symbol

PDE11A

Additional PDE11A Products

Product Documents for PDE11A Antibody

Certificate of Analysis

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Product Specific Notices for PDE11A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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