Peptide5

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Connexin 43 mimetic peptides reduce swelling, astrogliosis and neuronal cell death after spinal cord injury.
   O'Carroll et al.
   Cell.Commun.Adhes., 2008;15:27
2. Characterisation of Peptide5 systemic administration for treating traumatic spinal cord injured rats.
   Mao et al.
   Exp.Brain.Res., 2017;235:3033
3. Characterising the mode of action of extracellular Connexin43 channel mimetic peptides in an in vitro ischemia injury model.
   Kim et al.
   Biochem.Biophys.Acta., 2017;1861:68
4. Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice.
   Tonkin et al.
   Exp.Neurol., 2017;300:1

Product Datasheets