Recombinant Human PGAM2 His Protein

Novus Biologicals | Catalog # NBP1-99092

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
View all PGAM2 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-253 of Human PGAM2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MATHRLVMVR HGESTWNQEN RFCGWFDAEL SEKGTEEAKR GAKAIKDAKM EFDICYTSVL KRAIRTLWAI LDGTDQMWLP VVRTWRLNER HYGGLTGLNK AETAAKHGEE QVKIWRRSFD IPPPPMDEKH PYYNSISKER RYAGLKPGEL PTCESLKDTI ARALPFWNEE IVPQIKAGKR VLIAAHGNSL RGIVKHLEGM SDQAIMELNL PTGIPIVYEL NKELKPTKPM QFLGDEETVR KAMEAVAAQG KAK

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

30.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PGAM2 His Protein

SDS-PAGE: Recombinant Human PGAM2 His Protein [NBP1-99092]

SDS-PAGE: Recombinant Human PGAM2 His Protein [NBP1-99092]

SDS-Page: PGAM2 Protein [NBP1-99092] - 15% SDS-PAGE (3 ug).

Formulation, Preparation, and Storage

NBP1-99092
Formulation 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1 M NaCl, 1 mM DTT
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PGAM2

PGAM2, also known as phosphoglycerate mutase 2, belongs to the phosphoglycerate mutase family. Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. Recombinant human PGAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

BPG-dependent PGAM 2, EC 3.1.3.13, EC 5.4.2.1, EC 5.4.2.4, Muscle-specific phosphoglycerate mutase, PGAM-MGSD10, PGAMMMGC88743, phosphoglycerate mutase 2, phosphoglycerate mutase 2 (muscle), Phosphoglycerate mutase isozyme M

Gene Symbol

PGAM2

Additional PGAM2 Products

Product Documents for Recombinant Human PGAM2 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human PGAM2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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