Recombinant Human PGL2 His Protein

Name: Recombinant Human PGL2 His Protein
Brand: Novus Biologicals
SKU: NBP2-22834
Price: 329 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-22834

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all PGL2 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 30-166 of Human PGL2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSSFRRFYR GDSPTDSQKD MIEIPLPPWQ ERTDESIETK RARLLYESRK RGMLENCILL SLFAKEHLQH MTEKQLNLYD RLINEPSNDW DIYYWATEAK PAPEIFENEV MALLRDFAKN KNKEQRLRAP DLEYLFEKPR

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

19 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PGL2 His Protein

SDS-PAGE: Recombinant Human PGL2 His Protein [NBP2-22834]

SDS-Page: Recombinant Human PGL2 Protein [NBP2-22834]

Formulation, Preparation, and Storage

NBP2-22834

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.2 M NaCl, 30% glycerol, 1 mM DTT
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PGL2

SDHAF2 is a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Defects in SDHAF2 are the cause of hereditary paragangliomas type 2 (PGL2), also known as familial non-chromaffin paragangliomas type 2. Paragangliomas refer to rare and mostly benign tumors that arise from any component of the neuroendocrine system. Recombinant human SDHAF2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

C11orf79, FLJ20487, hSDH5, paraganglioma or familial glomus tumors 2, PGL2chromosome 11 open reading frame 79, SDH5SDH assembly factor 2, succinate dehydrogenase assembly factor 2, mitochondrial, succinate dehydrogenase complex assembly factor 2, Succinate dehydrogenase subunit 5, mitochondrial

Gene Symbol

SDHAF2

Additional PGL2 Products

Product Documents for Recombinant Human PGL2 His Protein

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Product Specific Notices for Recombinant Human PGL2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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