Philanthotoxin 74

  ( 1 citations )    
Product Datasheet
Catalog Number:2770
Alternate Names:PhTx-74
Chemical Name:(S)-N-[7-[(4-Aminobutyl)amino]heptyl]-4-hydroxy-α-[(1-oxobutyl)amino]benzenepropanamide dihydrochloride
Product Details
Citations (1)
Supplemental Products
Biological Activity
AMPA receptor antagonist. Non-selective homomeric GluR3 and GluR1 receptor antagonist (IC50 values are 263 and 296 nM respectively). Inhibits homomeric GluR3 and GluR1 with a 100-fold greater potency than heteromeric GluR1/2 and GluR2/3 receptors.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets

The citations listed below are publications that use Tocris products. Selected citations for Philanthotoxin 74 include:

1 Citations: Showing 1 - 1

  1. Calcineurin mediates synaptic scaling via synaptic trafficking of Ca2+-permeable AMPA receptors.
    Authors: Kim and Ziff
    PLoS Biol  2014;12:e1001900


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