Recombinant Human PINX1 His Protein

Novus Biologicals | Catalog # NBC1-26375

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-328 of Human PINX1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSMLAERRRK QKWAVDPQNT AWSNDDSKFG QRMLEKMGWS KGKGLGAQEH GATDHIKVQV KNNHLGLGAT INNEDNWIAH QDDFNQLLAE LNTCHGQETT DSSDKKEKKS FSLEEKSKIS KNRVHYMKFT KGKDLSSRSK TDLDCIFGKR QSKKTPEGDA SPSTPEENET TTTSAFTIQE YFAKRMAALK NKPQVPVPGS DISETQVERK RGKKINKEAT GKDVESYLQP KAKRHTEGKP ERAEAQERVA KKKSAPAEEQ LRGPCWDQSS KASAQDAGDH VQPPEGRDFT LKPKKRRGKK KLQKPVEIAE DATLEETLVK KKKKKDSK

Purity

>95%, by SDS-PAGE

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Predicted Molecular Mass

39.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PINX1 His Protein

Western Blot: Recombinant Human PINX1 His Protein [NBC1-26375]

Western Blot: Recombinant Human PINX1 His Protein [NBC1-26375]

Western Blot: PINX1 Protein [NBC1-26375]

Formulation, Preparation, and Storage

NBC1-26375
Formulation 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PINX1

PINX1(PIN2-interacting protein 1) is a ubiquitously expressed protein that localizes to nucleoli and telomere speckles. This protein contains a TID (telomerase inhibiting domain) domain which is capable of binding MCRS1, TERT and TERF1. PINX1 has been shown to be a potent telomerase inhibitor and putative tumor suppressor. Recombinant human PINX1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

FLJ20565, hepatocellular carcinoma-related putative tumor suppressor, Liver-related putative tumor suppressor, LPTLPinX1, LPTS67-11-3 protein, MGC8850, PIN2 interacting protein 1, PIN2/TERF1 interacting, telomerase inhibitor 1, PIN2/TERF1-interacting telomerase inhibitor 1, PIN2-interacting protein 1, Pin2-interacting protein X1, Protein 67-11-3, TRF1-interacting protein 1

Gene Symbol

PINX1

Additional PINX1 Products

Product Documents for Recombinant Human PINX1 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human PINX1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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