PIR 3.5

Tocris Bioscience | Catalog # 4212

Negative control of IPA 3 (Cat. No. 3622)
Tocris Bioscience
Discontinued Product
4212 has been discontinued. View all PAK Inhibitors products.

Key Product Details

Description

Negative control of IPA 3 (Cat. No. 3622)
View all PAK Inhibitors »

Product Description

PIR 3.5 is a negative control of IPA 3, a direct, non-competitive inhibitor of group I p21-activated kinase (Pak1).

Active Analog also available.

Product Specifications for PIR 3.5

Molecular Weight

350.45

Formula

C20H14O2S2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

6,6'-Dithiodi-2-naphthtol

CAS Number

6088-51-3

PubChem ID

22463

InChI Key

AHXGXXJEEHFHDK-UHFFFAOYSA-N

SMILES

OC1=CC=C2C(C=CC(SSC3=CC(C=CC(O)=C4)=C4C=C3)=C2)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 26.28 75
Ethanol 3.5 10

Preparing Stock Solutions for PIR 3.5

The following data is based on the product molecular weight 350.45.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 3.80 mL 19.02 mL 38.05 mL
3.75 mM 0.76 mL 3.80 mL 7.61 mL
7.5 mM 0.38 mL 1.90 mL 3.80 mL
37.5 mM 0.08 mL 0.38 mL 0.76 mL

Calculators

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

Product Documents for PIR 3.5

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PIR 3.5

For research use only

Related Research Areas

Intracellular Kinases

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