8 results for "PAK Inhibitors" in Products

PAK Inhibitors

PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members....

Show More

Group I PAK inhibitor

Chemical Name: 1,1'-Dithiodi-2-naphthtol
Purity: ≥96%
Group I PAK inhibitor
Loading...

Potent PAK inhibitor; brain penetrant and orally bioavailable

Chemical Name: 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
Purity: ≥98%
Potent PAK inhibitor; brain penetrant and orally bioavailable
Loading...

Potent group I PAK inhibitor

Chemical Name: 6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Purity: ≥98%
Potent group I PAK inhibitor
Loading...

High affinity group I PAK inhibitor

Chemical Name: 8-[(trans-5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one
Purity: ≥98%
High affinity group I PAK inhibitor
Loading...

Negative control of NVS PAK1 1 (Cat. No. 6132)

Chemical Name: (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N,N-dimethylpyrrolidine-1-carboxamide
Purity: ≥98%
Negative control of NVS PAK1 1 (Cat. No. 6132)
Loading...

Potent PAK4 inhibitor; orally available

Chemical Name: N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide dihydrochloride
Purity: ≥98%
Potent PAK4 inhibitor; orally available
Loading...

Potent and selective PAK1 inhibitor

Chemical Name: (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N-isopropylpyrrolidine-1-carboxamide
Purity: ≥98%
Potent and selective PAK1 inhibitor
Loading...

Highly potent PAK1 and PAK2 inhibitor

Chemical Name: 2-[[[2-[[3-(Ethylsulfonyl)-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-fluoro-4-pyrimidinyl][5-(hydroxymethyl)-2-methylphenyl]amino]methyl]benzonitrile
Purity: ≥98%
Highly potent PAK1 and PAK2 inhibitor
Loading...
Results Per Page
5 10 25 50
  • / 1