PKA C (pan) [p Thr197] Antibody (24GB1650)

Novus Biologicals | Catalog # NBP3-50611

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 24GB1650
View all PKA C (pan) Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Phospho-PKA C (pan) (Thr197) (Uniprot: P22612/P17612/P22694)

Modification

p Thr197

Specificity

This antibody detects endogenous levels of PRKACG/PRKACA/PRKACB only when phosphorylated at T197

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for PKA C (pan) [p Thr197] Antibody (24GB1650)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PKA C (pan)

The cAMP-dependent protein kinase (PKA) holoenzyme is composed of two regulatory and two catalytic subunits, designated PKA R and PKA C, respectively. Upon PKA R subunit binding to the second messenger cAMP, active PKA C subunits are released, initiating a phosphorylation cascade that regulates such cellular functions as metabolism, ion transport, and gene transcription. Catalytic PKA subunit isoforms, Cα, Cβ and, in humans, Cγ, have been identified.

Long Name

cAMP-dependent Protein Kinase Catalytic Subunit

Alternate Names

CAFD1, PKACA, PPNAD4

Gene Symbol

PRKACA

Additional PKA C (pan) Products

Product Documents for PKA C (pan) [p Thr197] Antibody (24GB1650)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for PKA C (pan) [p Thr197] Antibody (24GB1650)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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