PKR Antibody (S08-2C8)

Name: PKR Antibody (S08-2C8)
Brand: Novus Biologicals
SKU: NBP3-19517
Price: 569 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-19517

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-2C8 expressed in HEK293

View all PKR Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human PKR (Uniprot # P19525)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

74 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PKR Antibody (S08-2C8)

Western Blot: PKR Antibody (S08-2C8) [NBP3-19517]

Western Blot: PKR Antibody (S08-2C8) [NBP3-19517] - Western blot detection of PKR in K562, Hela cell lysates using NBP3-19517 (1:1000 diluted). Predicted band size: 62kDa. Observed band size: 74kDa.

Immunocytochemistry/ Immunofluorescence: PKR Antibody (S08-2C8) [NBP3-19517]

Immunocytochemistry/Immunofluorescence: PKR Antibody (S08-2C8) [NBP3-19517] - Immunofluorescence of PKR (green) in Hela cells using NBP3-19517 at dilution 1/200, and DAPI (blue)

Immunohistochemistry-Paraffin: PKR Antibody (S08-2C8) [NBP3-19517]

Immunohistochemistry-Paraffin: PKR Antibody (S08-2C8) [NBP3-19517] - Immunohistochemistry of PKR in paraffin-embedded Human Cholangiocarcinoma using NBP3-19517 at dilution 1/2

Applications for PKR Antibody (S08-2C8)

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/20

Immunohistochemistry

1/20

Western Blot

1/2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PKR

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses.

Long Name

Protein Kinase R

Alternate Names

EIF2AK2, P68 Kinase, PPP1R83, PRKR, Protein Kinase R

Gene Symbol

EIF2AK2

Additional PKR Products

Product Documents for PKR Antibody (S08-2C8)

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Certificate of Analysis

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Product Specific Notices for PKR Antibody (S08-2C8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Intracellular Kinases

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