PKUMDL WQ 2201 New
Chemical Name: 2-Chloro-4-[5-[[2-[(ethylamino)thioxomethyl]hydrazinylidene]methyl]-2-furanyl]benzoic acid
Biological ActivityNegative allosteric modulator of phosphoglycerate dehydrogenase (PHGDH) (IC50 = 35.7 μM). Displays dose-dependent suppression of cell viability in a range of cancer cell lines. Inhibits tumor growth in a xenograft mouse model.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Rational design of selective allosteric inhibitors of PHGDH and serine synthesis with anti-tumor activity.
Wang et al.
Cell Chem.Biol., 2017;24:55
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for PKUMDL WQ 2201
There are currently no reviews for this product. Be the first to review PKUMDL WQ 2201 and earn rewards!
Have you used PKUMDL WQ 2201?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image