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PMSF

Catalog #: 4486 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4486/50
PMSF | CAS No. 329-98-6 | Additional Synthetic Protease Inhibitors
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Description: Non-selective protease inhibitor; also blocks anandamide metabolism

Chemical Name: Phenylmethylsulfonyl fluoride

Purity: ≥98%

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Biological Activity

PMSF is a non-selective protease inhibitor; irreversibly sulfonates key active site serine residues in serine proteases, acetylcholinesterases, and thiol proteases. Blocks metabolism of anandamide (Cat. No. 1339) in a rodent model of cannabimimetic activity. Unstable in water (t1/2 ~ 60 mins at pH 7.5). Brain penetrant.

Technical Data

M.Wt:
174.19
Formula:
C7H7FO2S
Solubility:
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
329-98-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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