Poly(I:C)

Catalog # Availability Size / Price Qty
4287/10
4287/50
Toll-like Receptor Agonists Small Molecule
1 Image
Description: TLR3 agonist

Chemical Name: Polyinosinic-polycytidylic acid sodium salt

Product Details
Citations (1)
Supplemental Products
Reviews (1)

Biological Activity

Synthetic double-stranded RNA (dsRNA); Toll-like receptor 3 (TLR3) agonist. Aids generation of stable, mature dendritic cells in combination with TLR8 agonist CL 075. Transfection into NIT-1 β cells induces β-cell apoptosis. Immunostimulant.

To prevent denaturation, this product should be reconstituted in solutions with physiological salt concentrations.

Technical Data

Formula:
(C10H13N4O8P)x.(C9H14N3O8P)x
Solubility:
Soluble to 3 mg/ml in water
Storage:
Store at -20°C
CAS No:
24939-03-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:
  • To prevent denaturation this product should be reconstituted in solutions with physiological salt concentrations.

Product Datasheets

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Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Citation for Poly(I:C)

The citations listed below are publications that use Tocris products. Selected citations for Poly(I:C) include:

1 Citation: Showing 1 - 1

FAQs

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Reviews for Poly(I:C)

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Good product
By Anonymous on 04/24/2018
Species: Human

I used this product to activate TLR3.


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