PP 3

Catalog # Availability Size / Price Qty
2794/10
PP 3 | CAS No. 5334-30-5 | Src Family Kinase Inhibitors
1 Image
Description: Negative control for PP 2 (Cat. No. 1407)

Chemical Name: 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Purity: ≥98%

Product Details
Citations (7)
Supplemental Products
Reviews

Biological Activity

Negative control for the Src kinase inhibitor, PP 2. Inhibits EGFR kinase (IC50 = 2.7 μM).

Active Analog also available.

Technical Data

M.Wt:
211.22
Formula:
C11H9N5
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
5334-30-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines.
    Traxler et al.
    J.Med.Chem., 1997;40:3601
  2. PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia.
    Hou et al.
    Neurosci.Letts., 2007;420:235

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for PP 3

The citations listed below are publications that use Tocris products. Selected citations for PP 3 include:

7 Citations: Showing 1 - 7

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for PP 3

There are currently no reviews for this product. Be the first to review PP 3 and earn rewards!

Have you used PP 3?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.