Catalog Number: 2794
Chemical Name: 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Biological Activity
Negative control for the Src kinase inhibitor PP 2 (Cat. No. 1407). Inhibits EGFR kinase (IC50 = 2.7 μM).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 25 mM in ethanol
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines.
    Traxler et al.
    J.Med.Chem., 1997;40:3601
  2. PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia.
    Hou et al.
    Neurosci.Letts., 2007;420:235
Tocris Small Molecules
Description Application Cat# Citations Images  

PP 2

1407 32  
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