Subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D-containing receptors (Ki
values are 0.096, 0.125, 0.31 and 0.55 μ
M for NR2C, NR2D, NR2B and NR2A subunits respectively).
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Sold under license from UNeMed Corporation.
Identification of subunit- and antagonist-specific amino acid residues in the N-methyl-D-aspartate receptor glutamate-binding pocket.
Kinarsky et al.
Structure-activity analysis of a novel NR2C/NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl)piperazine-2,3-dicarboxylic acid.
Feng et al.
Synthesis and pharmacology of N1-substituted piperazine-2,3-dicarboxylic acid derivatives acting as NMDA receptor antagonists.
Morley et al.
The citations listed below are publications that use Tocris products. Selected citations for PPDA include:
Showing Results 1 - 2 of 2