PPDA

  ( 4 citations )    
Product Datasheet
Catalog Number:2530
Chemical Name:(2S*,3R*)-1-(Phenanthren-2-carbonyl)piperazine-2,3-dicarboxylic acid
Product Details
Citations (4)
Reviews
Biological Activity
Subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D-containing receptors (Ki values are 0.096, 0.125, 0.31 and 0.55 μM for NR2C, NR2D, NR2B and NR2A subunits respectively).
Technical Data
  • M.Wt:
    378.38
  • Formula:
    C21H18N2O5
  • Solubility:
    Soluble to 50 mM in 2eq. NaOH and to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    684283-16-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from UNeMed Corporation.
Product Datasheets
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for PPDA include:

4 Citations: Showing 1 - 4
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  1. Distinct molecular components for thalamic- and cortical-dependent plasticity in the lateral amygdala.
    Authors: Mirante Et al.
    Autophagy  2014;7:62
  2. Altered gamma oscillations during pregnancy through loss of δ subunit-containing GABA(A) receptors on parvalbumin interneurons.
    Authors: Ferando and Mody
    Front Neural Circuits  2013;7:144
  3. Pharmacological evidence that D-aspartate activates a current distinct from ionotropic glutamate receptor currents in Aplysia californica.
    Authors: Carlson Et al.
    Brain Behav  2012;2:391
  4. Unique ionotropic receptors for D-aspartate are a target for serotonin-induced synaptic plasticity in Aplysia californica.
    Authors: Carlson and Fieber
    Comp Biochem Physiol C Toxicol Pharmacol  2012;155:151

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