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Catalog Number:4862
Chemical Name:4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride
Product Details
Supplemental Products
Reviews
Biological Activity
High affinity and selective P2Y14 antagonist (KB = 434 pM). Exhibits >10,000-fold selectivity for P2Y14 over other P2Y receptors. Inhibits UDP-glucose and MRS 2690-induced porcine pancreatic artery contraction ex vivo. Also blocks UDP-glucose-induced chemotaxis of HL-60 leukemia cells in vitro.
High affinity and selective P2Y14 antagonist (KB = 434 pM). Exhibits >10,000-fold selectivity for P2Y14 over other P2Y receptors. Inhibits UDP-glucose and MRS 2690-induced porcine pancreatic artery contraction ex vivo. Also blocks UDP-glucose-induced chemotaxis of HL-60 leukemia cells in vitro.
Technical Data
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M.Wt:511.96
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Formula:C29H24F3NO2.HCl
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Solubility:Soluble to 100 mM in DMSO and to 20 mM in ethanol
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Purity:>98
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Storage:Store at -20°C
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Product Datasheets
VersaClone cDNA Plasmids
Description
Application
Cat#
Citations
Images
Human P2Y14/GPR105 (NP_055694) VersaClone cDNA
RDC0378
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Mouse P2Y14/GPR105 (NP_573463) VersaClone cDNA
RDC0672
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