T. gondii profilin-like protein is an 18 kDa protozoan molecule that activates TLR11. Activation of TLR11 induces IL-12 production in dendritic cells and promotes innate resistance to protozoan infection. While rodents have a functional TLR11 gene, the human counterpart is silent due to a mutation. Functionally, profilins are actin binding proteins that regulate the polymerization of actin during movement.
Profilin-like Protein Antibody [DyLight 405]
Novus Biologicals | Catalog # AF3860E
Key Product Details
Species Reactivity
T. gondii
Applications
Western Blot
Label
DyLight 405 (Excitation = 400 nm, Emission = 420 nm)
Antibody Source
Polyclonal Goat IgG
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Product Specifications
Immunogen
E. coli-derived recombinant T. gondii Profilin-like Protein
Ser2-Tyr163
Accession # AAX47289
Ser2-Tyr163
Accession # AAX47289
Reactivity Notes
T. gondii
Specificity
Detects T. gondii Profilin-like Protein in direct ELISAs and Western blots.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Profilin-like Protein Antibody [DyLight 405]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Profilin-like Protein
Alternate Names
Profilin like Protein, rPFTG
Additional Profilin-like Protein Products
Product Documents for Profilin-like Protein Antibody [DyLight 405]
Product Specific Notices for Profilin-like Protein Antibody [DyLight 405]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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