PROP1 Antibody

Novus Biologicals | Catalog # NBP1-44054

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
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Product Specifications

Immunogen

Peptide with sequence AERRRQAEKPKKGR-C corresponding to N-Terminus according to NP_006252.2.

Epitope

N-Terminus

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Applications for PROP1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000
Application Notes
WB: Preliminary experiments in human brain (cortex) lysates gave no specific signal but low background.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PROP1

PROP1 has both DNA-binding and transcriptional activation ability. Its expression leads to ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes, and caudomedial thyrotropes. Inactivating mutations in PROP1 result in deficiencies of luteinizing hormone (LH; MIM 152780), follicle-stimulating hormone (FSH; MIM 136530), growth hormone (GH; MIM 139250), prolactin (PRL; MIM 176760), and thyroid-stimulating hormone (TSH; MIM 188540). See combined pituitary hormone deficiency (CPHD; MIM 262600).[supplied by OMIM]

Alternate Names

CPHD2, homeobox protein prophet of Pit-1, Pituitary-specific homeodomain factor, PROP paired-like homeobox 1, PROP-1, prophet of Pit1, paired-like homeodomain transcription factor

Entrez Gene IDs

5626 (Human)

Gene Symbol

PROP1

Additional PROP1 Products

Product Documents for PROP1 Antibody

Certificate of Analysis

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Product Specific Notices for PROP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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