Recombinant Human Protein Phosphatase 1C gamma His Protein

Novus Biologicals | Catalog # NBP2-59582

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

Enzyme Activity, SDS-PAGE
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Product Specifications

Description

A bioactive recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-323 of Human Protein Phosphatase 1C gamma

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MADLDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLK ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVLGWGEND RGVSFTFGAE VVAKFLHKHD LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAE KKKPNATRPV TPPRGMITKQ AKK

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

39.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Specific activity is > 700 units/mg, and is defined as the amount of enzyme that hydrolyze 1.0 nmole of p-nitrophenyl phosphate (pNPP) per minute at pH 7.5 at 37C.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Protein Phosphatase 1C gamma His Protein

SDS-PAGE: Recombinant Human Protein Phosphatase 1C gamma His Protein [NBP2-59582]

SDS-PAGE: Recombinant Human Protein Phosphatase 1C gamma His Protein [NBP2-59582]

SDS-Page: Recombinant Human Protein Phosphatase 1C gamma His Protein [NBP2-59582] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation, and Storage

NBP2-59582
Formulation 20 mM Tris-HCl buffer (pH8.0), 50% glycerol, 0.2 M NaCl, 2 mM DTT
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Protein Phosphatase 1C gamma

Protein Phosphatase 1C gamma is encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternate Names

EC 3.1.3.16, PP-1G, PP1gamma, PPP1G, protein phosphatase 1, catalytic subunit, gamma isoform, protein phosphatase 1, catalytic subunit, gamma isozyme, Protein phosphatase 1C catalytic subunit, serine/threonine phosphatase 1 gamma, serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Gene Symbol

PPP1CC

Additional Protein Phosphatase 1C gamma Products

Product Documents for Recombinant Human Protein Phosphatase 1C gamma His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human Protein Phosphatase 1C gamma His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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