Ready-to-Use Cytokine Formats
Liquid, process-sized, & closed process options for GMP cytokines are now available to fit your workflow needs!
Liquid Cytokines: Eliminate Reconstitution Steps
Designed to simplify your complex processes, liquid frozen cytokines streamline your workflow, simplify your protocol, and achieve greater research efficiencies by eliminating the reconstitution step. This removes the risk of errors associated with reconstitution plus eliminates the need to maintain a sterile reconstitution buffer. Simply thaw and add to your cell culture.
Protein stability is paramount to ensure safety, bioactivity, and minimal variability. With this in mind, we have optimized protein concentrations and conducted extensive stability testing. You can rest assured of the potency and effectiveness of the liquid cytokines over time, ensuring consistent performance and reliable outcomes for your cell therapy.
Process-Sized Cytokines: Eliminate Aliquoting Steps
Process-sized vials remove the need to aliquot your cytokines, allowing for higher patient safety and reduced hands-on technician time. These single-use vials have been process-optimized and are compatible with any immune cell manufacturing system, including ScaleReady G-Rex® bioreactors. Simply use a syringe to reconstitute cytokines in the vial and add to your cell culture.
- Simplify your cell manufacturing workflow
- Reduce manual touchpoints
- Eliminate aliquoting variability
ProPak: The Benefits of Liquid and Process-Sized GMP Cytokines
ProPak GMP cytokines offer a "best of both" approach: liquid cytokines in process sizes, with the additional benefit of weldable bags supporting a closed process workflow. GMP IL-2, IL-7, and IL-15 are delivered through process-sized bags with weldable tubing and are compatible with bagged media for use in a 1 L bioreactor, such as the G-Rex.
Learn how to add these GMP cytokines to your media in the ProPak User Manual.
| Protein Name | Liquid | Process-Sized | ||
| RUO Vial | GMP Vial | GMP Vial (Lyophilized) | GMP ProPak™ (Liquid in Bag) | |
| IL-2 | 50 μg, 1 mg | 50 μg, 1 mg | 10 µg, 150k IU, or 3M IU | |
| IL-7 | 25 μg | 25 μg | 10 µg | 10 µg |
| IL-15 | 25 μg | 25 μg | 10 µg | 10 µg |
| IL-21 | 25 μg, 1 mg | 25 μg, 1 mg | ||
Liquid formulations for these proteins are currently available to ship to the United States, Canada, and Europe. We are working to expand shipping to other parts of the world.
| IL-2 | Liquid | Lyophilized |
|---|---|---|
| Formulation | 0.50 mg/mL, 0.2 μm filtered solution in sodium acetate | Lyophilized from a 0.2 μm filtered solution in sodium acetate with Trehalose |
| Stability | A minimum of 6 months when stored at ≤ -65 °C as supplied | A minimum of 12 months when stored at ≤ -20 °C as supplied |
| Pack Size | 10 µg, 150k IU, or 3M IU bag, 50 μg, 1 mg | 50 μg, 1 mg |
| IL-7 | Liquid | Lyophilized |
|---|---|---|
| Formulation | 0.50 mg/mL, 0.2 μm filtered solution in PBS | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose |
| Stability | A minimum of 6 months when stored at ≤ -65 °C as supplied | A minimum of 12 months when stored at ≤ -20 °C as supplied |
| Pack Size | 10 µg bag (1L process size), 25 μg | 10 µg (1L process size), 25 μg, 1 mg |
| IL-15 | Liquid | Lyophilized |
|---|---|---|
| Formulation | 0.50 mg/mL, 0.2 μm filtered solution in PBS | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose |
| Stability | A minimum of 6 months when stored at ≤ -65 °C as supplied | A minimum of 12 months when stored at ≤ -20 °C as supplied |
| Pack Size | 10 µg bag (1L process size), 25 μg | 10 µg (1L process size), 25 μg, 1 mg |
| IL-21 | Liquid | Lyophilized |
|---|---|---|
| Formulation | 0.50 mg/mL, 0.2 μm filtered solution in PBS | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose |
| Stability | A minimum of 6 months when stored at ≤ -65 °C as supplied | A minimum of 12 months when stored at ≤ -20 °C as supplied |
| Pack Size | 25 μg, 1 mg | 25 μg, 1 mg |
Stability data for liquid frozen cytokines is available on request.