PSB 0777 ammonium salt

Key Product Details

Product Description

PSB 0777 ammonium salt is a potent adenosine A_2A receptor full agonist (K_i = 44.4 nM for rat brain striatal A_2A receptors). Exhibits subtype selectivity for A_2A receptors over A₁, A_2B and A₃ receptors (K_i ≥ 10 000 nM for rat A₁, human A_2B and human A₃ receptors). Potentiates acetylcholine-induced contractions in ex vivo rat ileum/jejunum segments.

Product Specifications for PSB 0777 ammonium salt

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for PSB 0777 ammonium salt

The following data is based on the product molecular weight 500.55.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.00 mL	9.99 mL	19.98 mL
5 mM	0.40 mL	2.00 mL	4.00 mL
10 mM	0.20 mL	1.00 mL	2.00 mL
50 mM	0.04 mL	0.20 mL	0.40 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• El-Tayeb Development of polar adenosine A_2A receptor agonists for inflammatory bowel disease: synergism with A_2B antagonists. ACS Med.Chem.Lett. 2012 PMID: 24900277

Product Documents for PSB 0777 ammonium salt