PTP beta/zeta/PTPRZ Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-80916

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all PTP beta/zeta/PTPRZ Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LFRHLHTVSQILPQVTSATESDKVPLHASLPVAGGDLLLEPSLAQYSDVLSTTHAASETLEFGSESGVLYKTLMFSQVEPPSSDAMMHARSSGPEPSYALSDNEGSQHIFTVSYSSAIPVHDSVGVTYQGSLFSGPSHIPIPKSSLIT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTP beta/zeta/PTPRZ Antibody - BSA Free

Western Blot: PTP beta/zeta/PTPRZ Antibody [NBP1-80916]

Western Blot: PTP beta/zeta/PTPRZ Antibody [NBP1-80916]

Western Blot: PTP beta/zeta/PTPRZ Antibody [NBP1-80916] - Analysis in human brain tissue.
Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916]

Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916]

Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916] - Staining in human cerebral cortex and liver tissues. Corresponding PTPRZ1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916]

Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916]

Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916] - Staining of human cerebral cortex shows strong cytoplasmic positivity in a subset of neuronal cells.
Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916]

Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916]

Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916] - Staining of human glioma shows moderate cytoplasmic positivity in tumor cells.
Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916]

Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916]

Immunohistochemistry-Paraffin: PTP beta/zeta/PTPRZ Antibody [NBP1-80916] - Staining of human liver shows no positivity as expected.

Applications for PTP beta/zeta/PTPRZ Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTP beta/zeta/PTPRZ

PTPRB is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is a transmembrane PTP. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins, which are critical in physiological and pathological events such as cell migration, adhesion and transformation.

Long Name

Protein Tyrosine Phosphatase beta/zeta

Alternate Names

HPTPZ, PTP18, PTPRZ, PTPRZ1, RPTPB

Entrez Gene IDs

5803 (Human)

Gene Symbol

PTPRZ1

UniProt

P23471

Additional PTP beta/zeta/PTPRZ Products

Product Documents for PTP beta/zeta/PTPRZ Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for PTP beta/zeta/PTPRZ Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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