Recombinant Human PTRH2 His Protein

Name: Recombinant Human PTRH2 His Protein
Brand: Novus Biologicals
SKU: NBP1-50914
Price: 419 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-50914

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all PTRH2 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 64-179 of Human PTRH2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MEYKMILVVR NDLKMGKGKV AAQCSHAAVS AYKQIQRRNP EMLKQWEYCG QPKVVVKAPD EETLIALLAH AKMLGLTVSL IQDAGRTQIA PGSQTVLGIG PGPADLIDKV TGHLKLY

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

14.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PTRH2 His Protein

SDS-PAGE: Recombinant Human PTRH2 His Protein [NBP1-50914]

SDS-Page: Recombinant Human PTRH2 Protein [NBP1-50914] - 15 % SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-50914

Formulation	20 mM Tris-HCl buffer (pH 8.0), 10% glycerol, 1 mM DTT
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTRH2

PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1, is a mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondria to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. The natural substrate for PTRH2 may be petidyl-tRNAs which drop off the ribosome during protein synthesis. Recombinant human PTRH2 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

Bcl-2 inhibitor of transcription 1, BIT1CGI-147, EC 3.1.1.29, mitochondrial, peptidyl-tRNA hydrolase 2, PTH2FLJ32471

Gene Symbol

PTRH2

Additional PTRH2 Products

Product Documents for Recombinant Human PTRH2 His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human PTRH2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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