(Z)-Pugnac

  ( 1 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:3384
Chemical Name:O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino-Z-N-phenylcarbamate
Product Details
Citations (1)
Reviews
Biological Activity
O-GlcNAc-β-N-acetylglucosaminidase (O-GlcNAcase) and β-hexosaminidase inhibitor (Ki values are 46 and 36 nM respectively) that increases O-GlcNAc levels ~ 2-fold in HT29 cells. Z-linked isomer is more potent than the E isomer.
Technical Data
  • M.Wt:
    353.33
  • Formula:
    C15H19N3O7
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at -20°C
  • CAS No:
    132489-69-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for (Z)-Pugnac include:

1 Citations: Showing 1 - 1

  1. O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity.
    Authors: Jo Et al.
    Oncotarget  2016;7:57186

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Average Rating: 5 (Based on 1 review)

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