The CA125 antigen, also known as MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. Expression of isoforms, proteolytic cleavage, and heavy N- and O- linked glycosylation produce forms of human CA125 that can vary from 200-5000 kDa in size. It inhibits NK cell activity, which is thought to contribute to immune evasion in peritoneal cancer and pregnancy.
Quantikine Immunoassay Control Set 765 for Human CA125/MUC16
R&D Systems | Catalog # QC56
For use with catalog number DCA125
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Key Product Details
Species
Human
Applications
Control
Product Summary for Quantikine Immunoassay Control Set 765 for Human CA125/MUC16
INTENDED USE & DESCRIPTION
For use as quantitative controls for the determination of cytokine concentrations in biological fluids. Concentrations have been assigned using R&D Systems’ Quantikine® kits. Controls are prepared in a buffered protein solution with preservatives. They contain recombinant human cytokines at low, medium and high concentrations. Controls are supplied lyophilized.
STORAGE & STABILITY
Unreconstituted Controls should be stored at 2-8 °C and are stable for at least 6 months from date of receipt. Depending on the analyte of interest, reconstituted controls may be stable when stored at < -20 °C. Users should evaluate the frozen stability of the controls in their application or discard after use.
REAGENT PREPARATION
Reconstitute each vial with the volume of deionized or distilled water indicated on the product datasheet.
PROCEDURE & EXPECTED VALUES
Controls should be assayed in the same manner as unknown specimens.
The acceptable ranges for the analytes in these controls are printed on the product datasheet. Due to possible variations in techniques and methodologies, it is recommended that each laboratory determine its own target range. Laboratories using other test systems should establish their own acceptable ranges as these assays may produce different values.
TECHNICAL HINTS & LIMITATIONS OF THE PROCEDURE
• The ranges were determined using R&D Systems’ Quantikine kits. If expected values are not obtained, verify that the lot numbers on the vials correspond with the lot numbers listed above and the correct volume of deionized or distilled water was used for reconstitution of the controls.
• The results obtained with these controls depend upon several factors associated with methods and instrumentation. Test systems other than those supplied by R&D Systems may result in values that differ from those printed on this product datasheet.
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Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: CA125/MUC16
Long Name
Ovarian Cancer Antigen CA125
Alternate Names
MUC16
Entrez Gene IDs
94025 (Human)
Gene Symbol
MUC16
Additional CA125/MUC16 Products
Product Documents for Quantikine Immunoassay Control Set 765 for Human CA125/MUC16
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Quantikine Immunoassay Control Set 765 for Human CA125/MUC16
For research use only
Related Research Areas
Customer Reviews for Quantikine Immunoassay Control Set 765 for Human CA125/MUC16 (2)
4.5 out of 5
2 Customer Ratings
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Verified Customer | Posted 05/22/2024
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Verified Customer | Posted 12/01/2023Used it for Human serum samples. Ran in duplicate. HQC, MQC, LQC as labelled in figure.
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