GDNF (Glial Cell Line-derived Neurotrophic Factor) is a secreted protein that promotes the survival of motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. It is produced by Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. GDNF binding to GFR alpha 1 induces the recruitment of Ret, NCAM-1/CD56, various integrins, Syndecan-3, or N-Cadherin. GDNF-based therapies show promise in several neurodegenerative disorders, particularly Parkinson’s disease.
Quantikine Immunoassay Control Set 991 for Human GDNF
R&D Systems | Catalog # QC253
For use with catalog number DGD00
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Key Product Details
Species
Human
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: GDNF
Long Name
Glial Cell line-derived Growth Factor
Alternate Names
ATF, HFB1-GDNF, HGDNF, HSCR3
Gene Symbol
GDNF
Additional GDNF Products
Product Documents for Quantikine Immunoassay Control Set 991 for Human GDNF
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Quantikine Immunoassay Control Set 991 for Human GDNF
For research use only
Related Research Areas
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Associated Pathways
