Antitumor agent; induces apoptosis and inhibits synthesis of heat shock proteins. Inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2
, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Can also activate Ca2+
channels and behaves as an agonist at estrogen (GPER) receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Kishimoto T et al.
Leucocyte Typing VI. Garland Publishing Inc. London.
The flavonol quercetin activates basolateral K+ channels in rat distal colon epithelium.
Cermak et al.
The effect of quercetin on the phosphorylation activity of the Rous sarcoma virus transforming gene product in vitro and in vivo.
Graziani et al.
Tyrosine protein kinase activity in the DMBA-induced rat mammary tumor: inhibition by quercetin.
Levy et al.
Quercetin as a novel activator of L-type Ca2+ channels in rat tail artery smooth muscle cells.
Saponara et al.
Induction of apoptosis by quercetin: involvement of heat shock protein.
Wei et al.
Cancer Res., 1994;54:4952
The citations listed below are publications that use Tocris products. Selected citations for Quercetin include:
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