Quercetin

Key Product Details

Product Description

Quercetin is an antitumor agent; induces apoptosis and inhibits synthesis of heat shock proteins. Inhibits many enzyme systems including tyrosine protein kinase, phospholipase A₂, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Can also activate Ca²⁺ and K⁺ channels and behaves as an agonist at estrogen (GPER) receptors. Blocks cellular entry by influenza A virus via an interaction with hemaglutinin. Inhibits SARS-CoV 3CL^pro (IC₅₀ = 73 μM). Targets and eliminates senescent cells. Orally bioavailable.

Product Specifications for Quercetin

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Quercetin

The following data is based on the product molecular weight 302.24.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.31 mL	16.54 mL	33.09 mL
5 mM	0.66 mL	3.31 mL	6.62 mL
10 mM	0.33 mL	1.65 mL	3.31 mL
50 mM	0.07 mL	0.33 mL	0.66 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 30 publications citing the usage of this product.

• Wu Quercetin as an antiviral agent inhibits influenza A virus (IAV) entry. Viruses 2015 PMID: 26712783
• Nguyen Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris. Biotechnol.Lett. 2012 PMID: 22350287
• Wei Induction of apoptosis by quercetin: involvement of heat shock protein. Cancer Res. 1994 PMID: 8069862
• Saponara Quercetin as a novel activator of L-type Ca²⁺ channels in rat tail artery smooth muscle cells. Br.J.Pharmacol. 2002 PMID: 11934824
• Levy Tyrosine protein kinase activity in the DMBA-induced rat mammary tumor: inhibition by quercetin. Biochem.Biophys.Res.Commun. 1984 PMID: 6091650
• Graziani The effect of quercetin on the phosphorylation activity of the Rous sarcoma virus transforming gene product in vitro and in vivo. J.Biochem. 1983 PMID: 6311542
• Cermak The flavonol quercetin activates basolateral K⁺ channels in rat distal colon epithelium. Br.J.Pharmacol. 2002 PMID: 11877325

Product Documents for Quercetin