Diacylglycerol (DAG) kinase inhibitor (IC
M); increases protein kinase C activity. Potentiates thrombin-induced platelet aggregation and induces neutrophil chemotaxis. Inhibits U46619-induced contractions in mouse aorta and porcine coronary artery.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet.
de Chaffoy de Courcelles et al.
A diacylglyerol kinase inhibitor, R59022, potentiates secretion by and aggregation of thrombin-stimulated human platelets.
Nunn and Watson
Neutrophil chemotaxis induced by the diacylglycerol kinase inhibitor R59022.
Boonen et al.
Novel diacylglycerol kinase inhibitor selectively suppressed an U46619-induced enhancement of mouse portal vein contraction under high glucose conditions.
Nobe et al.
The citations listed below are publications that use Tocris products. Selected citations for R 59-022 include:
1 Citations: Showing 1 - 1
Have you used R 59-022?
Submit a Review
Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.