R 59-022

  ( 1 citations )    
Product Datasheet
Catalog Number:2194
Chemical Name:6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one
Product Details
Citations (1)
Reviews
Biological Activity
Diacylglycerol (DAG) kinase inhibitor (IC50 = 2.8 μM); increases protein kinase C activity. Potentiates thrombin-induced platelet aggregation and induces neutrophil chemotaxis. Inhibits U46619-induced contractions in mouse aorta and porcine coronary artery.
Technical Data
  • M.Wt:
    459.58
  • Formula:
    C27H26FN3OS
  • Solubility:
    Soluble to 20 mM in ethanol and to 50 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    93076-89-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for R 59-022 include:

1 Citations: Showing 1 - 1

  1. Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti.
    Authors: Conley Et al.
    Nature  2015;352:53

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