12 results for "Lipid Metabolism Inhibitors" in Products
Lipid Metabolism Inhibitors
When glucose supplies are low, the body is able to draw upon lipids as an alternative energy source. Lipids are generally stored as triglycerides and the first step in lipid metabolism is the conversion to glycerol and fatty acids. Glycerol (dihydroxyacetone phosphate) can enter the glycolysis pathway, and proceed to the Krebs cycle and oxidative phosphorylation. Fatty acids are converted to acetyl CoA, which can directly enter the Krebs cycle and subsequently oxidative phosphorylation. Each ...
Selective fatty acid desaturase 2 inhibitor
| Chemical Name: | α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile |
| Purity: | ≥95% |
Cell permeable inhibitor of SREBP activation
| Chemical Name: | 4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridine hydrobromide |
| Purity: | ≥97% |
Diacylglycerol lipase inhibitor
| Alternate Names: | U 57908 |
| Chemical Name: | O,O'-[1,6-Hexanediylbis(iminocarbonyl)]dioxime cyclohexanone |
| Purity: | ≥95% |
Potent fatty acid synthase inhibitor; proapoptotic
| Alternate Names: | trans-C 75 |
| Chemical Name: | (2R*,3S*)-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid |
| Purity: | ≥94% |
Competitive inhibitor of SREBP site 1 protease
| Chemical Name: | 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide dihydrochloride |
| Purity: | ≥97% |
SCD-1 inhibitor
| Alternate Names: | NSC 14613 |
| Chemical Name: | 4-Pyridinecarboxylic acid 2-phenylhydrazide |
| Purity: | ≥99% |
2,3-Oxidosqualene cyclase (OSC) inhibitor; blocks cholesterol synthesis
| Chemical Name: | (4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone |
| Purity: | ≥98% |
Inhibitor of phosphatidylcholine transfer protein (PC-TP)
| Chemical Name: | 2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide |
| Purity: | ≥98% |
Potent acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor
| Chemical Name: | 1,4-Dihydro-1'-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4'-piperidin]-7(6H)-one |
| Purity: | ≥98% |
Potent human fatty acid synthase (hFASN) inhibitor
| Chemical Name: | 4-[4-(5-Benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one |
| Purity: | ≥98% |
Potent and reversible fatty acid desaturase 1 inhibitor; orally bioavailable
| Chemical Name: | N-[2-[[3,4-Dihydro-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]thio]ethyl]acetamide |
| Purity: | ≥98% |
Potent microsomal triglyceride transfer protein (MTP) inhibitor
| Chemical Name: | N-(2,2,2-Trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide methanesulfonate |
| Purity: | ≥98% |
