FGL2 (fibrinogen-like protein 2), also called fibroleukin, is a 64-70 kDa secreted glycoprotein of the Fibrinogen-like superfamily. In the presence of acidic phospholipids and calcium, FGL2 has prothrombinase activity and acts as a procoagulant. In soluble form, FGL2 promotes T regulatory (Treg) activity and suppresses DC, T, and B cell immune reactivity, acting as an immune suppressor. A 260-280 aa FGL2 complex is thought to be a homotetramer.
Rat FGL2 (NP_445907.2) VersaClone cDNA
R&D Systems | Catalog # RDC3441
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: FGL2
Long Name
Fibrinogen-like 2
Alternate Names
Fibroleukin, T49
Gene Symbol
FGL2
UniProt
Additional FGL2 Products
Product Documents for Rat FGL2 (NP_445907.2) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Rat FGL2 (NP_445907.2) VersaClone cDNA
For research use only
Related Research Areas
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