Rat GnRHR (NP_112300) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Rat GnRHR (NP_112300) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: GnRHR

GnRHR is the receptor for type 1 gonadotropin-releasing hormone. GnRHR is a member of the seven-transmembrane, G protein-coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, GnRHR associates with G proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of GnRHR ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in GnRHR are a cause of hypogonadotropic hypogonadism (HH).

Long Name
Gonadotropin-releasing Hormone Receptor
Entrez Gene IDs
2798 (Human); 14715 (Mouse); 81668 (Rat)
Alternate Names
GnRH receptor; GnRHR; GnRH-R; GNRHR1; gonadotropin-releasing hormone (type 1) receptor 1; gonadotropin-releasing hormone receptor; GRHR; HH7; leutinizing-releasing hormone receptor; LHRHR; LHRHRleutinizing hormone releasing horomone receptor; LRHR; luliberin receptor; Luliberin; type I GnRH receptor


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