Rat Vanilloid R1/TRPV1 Alexa Fluor® 350-conjugated Antibody

Catalog # Availability Size / Price Qty
AF3066U-100UG

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Rat Vanilloid R1/TRPV1 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Rat
Specificity
Detects rat Vanilloid R1/TRPV1 in immunohistochemistry.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
KLH-coupled rat Vanilloid R1/TRPV1 synthetic peptide
RASLDSEESESPPQENSC
Accession # O35433
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Vanilloid R1/TRPV1

VR1, also known as TRPV1 (Transient Receptor Potential Vanilloid 1) and capsaicin receptor, is a 115 kDa integral membrane ion channel that has six transmembrane domains and contains intracellular N-and C-termini. It contributes to normal pain and temperature sensation and also has a “sensory-effector” function. By alternative splicing, at least three VR1 isoforms are known. The sequence of residues 4-21 of rat VR1 is 78% and 28% identical to that of mouse and human VR1, respectively.

Long Name
Vanilloid Receptor 1/Transient Receptor Potential Cation Channel 1
Entrez Gene IDs
7442 (Human); 193034 (Mouse); 83810 (Rat)
Alternate Names
Capsaicin Receptor; Osm-9-like TRP channel 1; OTRPC1; transient receptor potential cation channel subfamily V member 1; transient receptor potential cation channel, subfamily V, member 1; transient receptor potential vanilloid 1a; transient receptor potential vanilloid 1b; TRPV1; Vanilloid R1; Vanilloid receptor 1; vanilloid receptor subtype 1; VanilloidR1; VR1; VR1DKFZp434K0220

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